Abstract
On 18 men walking for hours on midsummer days without taking food and drink, general symptoms, sweating and changes in blood and urine were observed, special reference being taken to chloride balance and its regulation by the kidney.
1. The period of walking varied from 3 to 8 hours, and the total amount of sweat from 841 to 3675 g., with chloride concentration ranging from 0.050 to 0.239 per cent.
2. The Cl concentration of the sweat being strikingly less than that of the body fluid, the sweating must result in an excess of Cl in the body. But no increase in the Cl concentration of the blood was found, while the protein concentration of serum rose distinctly.
3. More or less amount of urine with Cl cncentrations varying from 0.674 to 1.262 per cent were discharged during sweating. The excess of Cl in the body was therefore compensated by renal function, partly but not completely.
4. Tentative discussion on other mechanisms of compensation was given.
