The Japanese Journal of Physiology
Print ISSN : 0021-521X
Effects of Low-sodium Solutions on the Calcium-dependent Slow Action Potentials in Potassium-depolarized Guinea-pig Ventricular Muscle
Minoru INAZAWATsuguhisa EHARAJun-ichi HASEGAWA
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1982 Volume 32 Issue 2 Pages 315-319

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Abstract
Lowering [Na]o, down to 50% of the normal concentration only slightly reduced the overshoot of the Ca-dependent slow action potentials in K-depolarized guinea-pig papillary muscles. The maximum rate of rise of the action potential also appeared to be independent of [Na]o. These results suggest that Na ions do not play a major role as charge carriers responsible for generation of the slow action potentials in this tissue.
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© Physiological Society of Japan
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