Abstract
In contrast to the decreased metabolism in non-hypoxiaacclimated (CT) rats, acute hypoxia (9.5 % O2) did not change the resting metabolism in hypoxia-acclimated (HX: 12 % O2 for 2 months) rats at 25°C. After β-adrenergic blockade, acute hypoxia greatly reduced the resting metabolism in HX rats. The calorigenic response to norepinephrine (0.4 mg·kg-1) during acute hypoxia was, however, identical with that observed in CT rats. These results suggest an enhanced β-adrenergic stimulation in HX rats during acute exposure to hypoxia.
