Nicotinic and Muscarinic Property of ACh Receptors on Cultured Brain Stem Neurons

Abstract

Using cultures of dissociated neurons from the lower brain stem of rat embryos, the receptor properties of cholinoceptive neurons were examined pharmacologically. Out of 89 neurons, 41 showed facilitation of unit discharges by the application of acetylcholine. These cholinoceptive neurons were proven to have both nicotinic and muscarinic properties.