Abstract
In the G-H cells of Onchidium oesophageal ganglia, L-glutamate (L-glu) elicited hyperpolarizations caused by an increase in potassium permeability.
To identify the chemical groups of the structure of the L-glu receptor, which is involved in the L-glu response, the effects of chemical modifications were studied. Modifications of SH, guanidino, COOH, or NH2 groups depressed L-glu response. The modification of other polar amino acid residues and phospholipids, however, did not have an effect on the L-glu responses.
