Cell-cycle-dependent Changes of the Negative Surface Charges in L₉₂₉ Cells

Abstract

The negative charges of cell surface were studied by the adsorption method of methylene blue in the synchronized cultures of L₉₂₉ cells and its spontaneously transformed cell strain. The negative surface charges of the transformed cells were twice those of the original cells through all cell cycle phases. The surface charges cell-cycle-dependently changed in both cell systems and there were two maximum peaks at early G₁ and S phase.