Influence of Arterial Occlusion on Hematocrit and Plasma Protein Concentration of Femoral Venous Blood in Rabbit

Abstract

The changes of venous outflow (Q_v), hematocrit (Hct), total plasma protein (T_p), electrolytes, crystalloid osmolality, P_O2, P_CO2, and pH were simultaneously measured in hindlimb preparation of anesthetized rabbits during 5min occlusion of the femoral artery and the abdominal aorta and during the reactive hyperemia. During the occlusion of the femoral artery, Q_v decreased to 66.4% at the end of the occlusion. Hct and T_p decreased slightly and then tended to progressively increase. P_O2 showed an increasing trend following an initial decrease. During the occlusion of the aorta, Q_O2 showed a continuous drop to 38.0%, while Hct and T_p declined to 95.4 and 93.8%, respectively. Q_v, Hct, and T_p showed increase after the release of the occlusion of the femoral artery and the aort . Crystalloid osmolality and K⁺ were observed to rise slightly. From these results it was suggested (1) that the increase of Hct and T_p which represents the hemoconcentration occurred during the reactive hyperemia and during the occlusion of the femoral artery, while the hemodilution occurred during the aortic occlusion, and (2) that the gradual increase of Hct and T_p during the occlusion of the femoral artery would be caused by the collateral blood flow.