Turbidity Change of the Mouse Adrenal Medulla Evoked by Acetylcholine Stimulation

Abstract

The turbidity of the mouse adrenal medulla was measured using a photodiode and a video system equipped with an image processor. Acetylcholine applied at concentrations of 30 to 100μM induced a slow decrease in turbidity by about 0.1% of the resting value. This response was suppressed by Cd-containing or Ca-deficient medium. These results and a video image suggested a structural change in the chromaffin cells associated with the secretory activity.