Abstract
The author applied thermal stimulation to electrochemical models immersing the core in the warmed solution and obtained relation between the temperature (T) and stimulating time (t) under various experimental conditions.
1. The T-t curve is approximately the same to strength-duration curve in the nerve or muscle, though there are some differences due to the kind of the solution or other conditions.2. In warming solution with recovering power, (t) for the same (T) becomesl onger according to the intensity of recovering power. But when the solution contains stimulating agent, (t) for the same (T) becomes shorter according to the magnitude of the agent contained.
3. When the thermal and electrical stimulation are applied in combination, they act either cooperatively or antagonisticaly according to the direction of the current.
4. Hydrogen ions contained in the warming solution produce remarkable differences in T-t-relation, its higher concentration brought shortening of (t) according to its rate. The concentration and kind of other positive ion have scarcely any influence on the T-t curve.
Discussing these results, the author obtained the following conclusions.
Excitation with thermal stimulation will be caused thus, that the movement of hydrogen ion is activated by the increase of temperature and increase of ionswhich penetrate the excitable membrane and results in loss of excitable membrane samely as in the case of electrical stimulation on the electrochemical model, but the ultimate establishment of this view must await the result of future studies.