Abstract
The influence of stimulation of the lumbar ventral root and the dorsal root on the distal colon has been investigated. The chief results thus obtained may be summarised as follows:
1) In anesthetized and unanesthetized dogs, peripheral stimulation of the ventral root (L2-L7) constantly caused an ihibitory effect of the distal colon, and the dorsal root stimulation (L2-L7) caused always a motor effect. However, the reverse effect did not occurred under any condition.
2) The effect of ventral stimulation was abolished after blocking the inferior mesenteric ganglion by application of nicotine or a C6-solution. However, the effect of dorsal root stimulation was not influenced by the block of the ganglion. This shows that the inhibitory fibers have nerve-cells in the inferior mesenteric ganglion, however, the motor nerve do not have any nerve-cell connections in it.
3) The motor effect is augmented by eserine solution and abolished by atropine.
