ELECTRICAL ACTIVITY OF SINGLE INTERNODE

Abstract

Evidences were presented showing that the internodes of myelinated fibres respond to externally applied outward current.
The responses are characterized by high threshold and graded nature in size.
Similar responses can be evoked from the juxta-nodal myelin-covered portions of a fibre.
Evidences were presented showing that the inward internodal membrane current accompanying normal conduction is an expression of the internodal activity.
It was concluded that the internode is excitable, but whether it propagates and whether it excites the adjacent node or not, are unknown.