The Japanese Journal of Physiology
Print ISSN : 0021-521X
THE EXPERIMENTAL NEUROSIS OF ALBINO RAT CAUSED BY EXCESSIVE TRAINING (TRAINING SEIZURE)
KAZUO ASAHINAFUJIKO KITAHARAMIYOKO YAMANAKA
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1959 Volume 9 Issue 2 Pages 171-177

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Abstract
With the application of continuous excessive swimming to albino rats, the symptoms of seizure similar to the audiogenic seizure and conditioned seizure are resulted and this is called “Training seizure”.
The seizure consists of hypo-and hyperkinetic states. Judging from various symptoms, a wide area of the cerebral cortex, brain stem, cerebellum and spinal cord seem to be affected. The weight of cerebrum and diencephalon does not change so much, while the weight of cerebellum and medulla oblongata falls.
In regard to K and Na in the brain, K increases in cerebellum and medulla oblongata and Na increases in cerebllum so that the ratio K/Na is low in cerebellum.
The histological changes of ganglionic cells are extreme in cerebral cortex, while the cells of cerebellum are stable against hard training.
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© Physiological Society of Japan
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