1959 Volume 9 Issue 3 Pages 322-326
Some discussions were made on the alteration of estrus cycle and histological changes in various organs caused by excessive training to albino rats.
In the lightly or moderately trained group, the sexual cycle rotates regularly and even if it had been irregular prior to exercise, it became regular with training. In heavily trained group, there occurred an irregularity in the sexual cycle associated with the conspicuous decrease in body-weight.
In general, most organs showed the figure of hyperfunction in the early stage of training and degeneration or atrophy in later stage. Among others, thymus is the most fragile tissue, and salivary gland and testicle gland are the most resistant tissues against excessive exercise. The histological changes in intestine and kidney were very severe for their comparatively slight functional disturbances.