Abstract
Systemic GABA caused a fall in blood pressure, some changes in respiration and facilitation on the flexor reflex. Further, it could facilitate knee jerk under some suppressive condition (for example, chlorpromazine-poisoning).
The site of action of GABA on the spinal reflex was also in the brain stem.
The authors assume that systemic GABA has a specific affinity to the re ticular system and it is not a mere inhibitory substance in the mammals.
