Abstract
We reported that the level of 17-ketosteroid sulfates (17-KS-S) in urine is related to adaptability to stress in humans. 17-KS-S, differing from 17-OHCS, shows the highest level in young healthy adults, decreases with aging and advancing illness and shows a lowered level under psychosocial stress. Concerning adaptability to stress in relation to meal, 1) In daily life, excess or deficiency of meal due to overload, whether it is psychological or physical, caused a decrease in the value of 17-KS-S, 2) In inpatients, a will to live caused for appetite to increase, accompanied by an increased value of 17-KS-S, suggesting an importance of meal in coping with stress.
