Japanese Journal of Psychosomatic Medicine
Online ISSN : 2189-5996
Print ISSN : 0385-0307
ISSN-L : 0385-0307
Special Issues / Psychogenic Fever and Functional Hyperthermia : Basic and Clinical Updates
Brown Fat Thermogenesis in Body Temperature and Body Fat Regulation : Lessons from Human Studies
Masayuki Saito
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2020 Volume 60 Issue 3 Pages 210-216

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Abstract

Mammals including humans have two types of fat tissue, white and brown adipose tissues. White fat is a site for energy storage, while brown fat is a specific site for non-shivering thermogenesis, thereby being involved in the regulation of body temperature in response to cold exposure and also to inflammatory and stressful stimuli. As brown fat also contributes to the regulation of whole-body energy expenditure and body fat content depending on its thermogenic activity, it gathers much attention as a therapeutic target for obesity. Here, I review our current understanding about human brown fat obtained from prospective studies using FDG-PET.

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© 2020 Japanese Society of Psychosomatic Medicine
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