Clinical Aspects of Functional Hyperthermia

Abstract

Fever and hyperthermia are different. This is the core knowledge for understanding functional hyperthermia, and thus appropriately diagnosing functional hyperthermia from patients with fever of unknown origin (FUO). Functional hyperthermia was originally excluded from classic FUO. However, in Japan, the value of being free from symptoms and pains is becoming more prevalent even in a condition that does not have a poor prognosis, and functional hyperthermia has become a relatively independent problem. To diagnose functional hyperthermia, after chronic inflammation is excluded, it is necessary that clinical judgment is made while examining diseases such as systemic lupus erythematosus, Sjögren syndrome, acquired idiopathic generalized anhidrosis, and familial Mediterranean fever. Unlike pediatric and adolescent hyperthermia, where selective serotonin reuptake inhibitors are more effective, treatment is extremely difficult in adults. The basic skeleton of treatment for adults is to identify first and then improve coexisting organic diseases. In order to improve hyperthermia as a subsequent psychosomatic stress, it is better to approach multiple factors in multiple ways, and psychosomatic intervention is important as a component.