Abstract
We reported a girl (14 years) with minimal change nephrotic syndrome who showed frequent reccurence during menstruation. The patient was first diagnosed as nephrotic syndrome at 4 years old. Thereafter, she experiensed reccurence of this syndrome frequently. Since she had steroid-dependent nephrotic syndrome, cyclosporin had been administreted to maintain a complete remission since 1996. Even though she was given a cyclosporin therapy, nephrotic syndrome was reccurent again during her first menstruation, but it disappeared spontaneously at the end of menstruation period. Thereafter, frequent relapse had been noticed concomitantly with her menstruation. Our observation may suggest the menstruation is one of the triggering factor for the reccurence of nephrotic syndrome.