Abstract
In July 1997, an outbreak of food poisoning due to the pathogenic Escherichia Coli (E. Coli) O-157 occurred in Sakai, Japan. We analyzed the longitudinal urine abnormalities of the E. Coli O-157 infected patients without hemolytic uremic syndrome. The 400 patients who were achieved urinary examination within one month after the onset are analyzed. Among the cases who were detected hematuria more than 1± within one month, 20% and 16.3% patients showed hematuria after one and two years later, respectively. Similarly, 25.5% and 16.2% patients showed proteinuria after one and two years later, respectively. These results suggested that, E. Coli O-157 infection might cause the long term urine abnormalities even without occurrence of hemolytic uremic syndrome.