A case of ANCA-associated glomerulonrphritis detected by school urinalysis screening

Abstract

 A 14-year-old girl was admitted because of proteinuria and hematuria that had persisted one year before. The serum BUN and creatinine level were increased and a high titer of ANCA was detected. Renal biopsy specimens revealed fibro-cellular crescentic glomerulonephritis with sclerosis. After steroid therapy combined with cyclophosphamide, mizoribin, dipyridamole, heparin and warfarin, renal function and pathological findings were improved. This present case demonstrates that early diagnosis and treatment are very important in the ANCA associated nephritis.