Abstract
We measured serum cystatin C (CysC) in 82 pateints consisting of 28 renal disease, 10 neurological disease (cerebral palsy), 35 endocrine disease (diabetes, obesity), and 9 cardiovasucular disease (congenital heart disease). All of then showed normal renal function assessed by estimated GFR more than 90 ml/min/1.73m2 by Schwartz formula. The mean serum CysC was renal disease 0.79±0.13 mg/L, neurological disease 0.66±0.14 mg/L, endocrine disease 0.79±0.15 mg/L, cardiovasucular disease 0.79±0.15 mg/L. Neurological disease was significantly low value as compared with renal disease and endocrine disease. There were 13 patients of serum CysC 0.9-1.0 mg/L and 7 patients of those were obesity. In degree of obesity, serum CysC was non-obesity (degree of obesity<20%) 0.75±0.16 mg/L, mild obesity (degree of obesity 20-30%) 0.76±0.11 mg/L, moderate obesity (degree of obesity 30-50%) 0.77±0.13 mg/L, severe obesity (degree of obesity<50%) 0.93±0.14 mg/L. The severe obesity patients was significantly high value as compared with other patients. Serum CysC was suggested to show low value in the nervous system disease (cerebral palsy) and high value in the severe obesity.
