Consideration on clinico-pathological grading systems of pediatric IgA nephropathy

(An interinstitutional collaborative study on pediatric IgA nephropathy by the Chugoku-shikoku society for pediatric nephrology)

Abstract

 There were some clinico-pathological grading systems of IgA nephropathy. The Committee of the Special Study Group on Progressive Glomeular Diseases, Ministry of Health, Labor and Welfare of Japan (MHLW) revised the clinical guidelines for IgA nephropathy, in 2002. The newly guideline of MHLW was in course of preparation, for adult. However, the old and new guidelines had not been verified enough, especially for the pediatric IgA nephropathy.
 This time, over 150 renal biopsies of pediatric IgA nephropathy were accumulated by corporation of The Chugoku-shikoku society for pediatric nephrology and analyzed by pathological guidelines. We explained the new and old guidelines of IgA nephropathy in Japan, and examined whether they were suitable or insufficient for the pathological evaluation of pediatric IgA nephropathy, including our data.