Abstract
We report a girl born at extremely-low birth (ELBW) developed proteinuria at six years of age. She was born at 25 weeks and one day of gestation with a birth weight of 624g. Proteinuria was found at six years of age by routine school urinalysis. Renal biopsy was performed at nine years of age. The renal biopsy findings showed diffuse increase in glomerular size without mesangial proliferation or glomerular sclerosis. Recently, increased risk of hypertension and microalbuminuria caused by the decreased number of glomerulus were reported in adult persons born at low birth-weight (LBW). We speculated that proteinuria was developed in early childhood because of the smaller number of glomerulus in this case born at ELBW as compared to the persons born at LBW. As the number of survivor of ELBW increases coupled with the advance in medicine, it is suspected that number of the cases who developed proteinuria at early childhood increases.
