A case of kidney graft failure due to nonadherence

questionnaire survey of nonadherence in adolescent kidney transplant patients

Abstract

 It has been reported that nonadherence to immunosuppressive drugs is associated with increased organ rejection episodes leading to graft loss.
 We report here a case of 13―year old boy who received kidney transplantation at the age of 7. He developed antibody―mediated rejection and graft failure due to nonadherence in the fourth year after renal transplantation.
 To evaluate nonadherence of kidney transplant patients in our hospital, we carried out a questionnaire survey with five questions. Adolescent kidney transplant recipients (n＝8) at the Niigata University Medical and Dental Hospital were enrolled in the study. Of the total 8 patients, 67.5% (5 patients) reported missing their immunosuppressive drugs over the past 1 month.
 It is necessary to perform education and support for adolescent patient continuously.