A Case of Lowe Syndrome Showing Progression of Acute Kidney Injury to End Stage Renal Disease and Requiring Maintenance Hemodialysis via a Long-Term Indwelling Catheter

Abstract

We experienced a patient with Lowe Syndrome in whom acute kidney injury failed to improve and advanced to end stage renal failure. The patient now requires maintenance hemodialysis with a long-term indwelling catheter. In this case, hemodialysis was initiated with the expectation that the patient would recover from the acute kidney injury. Unfortunately, the nephropathy advanced to end stage renal disease, forcing maintenance hemodialysis to be continued. It is rare that maintenance hemodialysis is used in cases of Lowe syndrome complicated by end stage renal disease, and this is the first case of a patient with Lowe syndrome receiving this treatment in Japan. The failure in recovery from acute kidney injury and early arrival at the end stage of renal disease in this case may be attributable to the presence of kidney fragility associated with Lowe syndrome.