Current medical treatment for monosymptomatic nocturnal enuresis

Abstract

Nearly 6.4% of children, 6 to 15 years of age, bother nocturnal enuresis, which is a second leading common chronic disorder next to allergies. Treatment for nocturnal enuresis is recommended for the children at the age of six or later. For the patients who are still enuretic after lifestyle advices, the active treatment is recommended. This comprises of desmopressin and alarm therapy or both. Other treatment including anti-cholinergics or tricyclic anti-depressants are options. We need to remind that tricyclic anti-depressants are cardiotoxic when used overdose. Japanese Society on Enuresis recently published the Treatment Guideline for Enuresis, which is the revised version of the one first come out in 2004. In this review article, we mention mainly the up-to-date treatment of monosymptomatic nocturnal enuresis followed by the new guideline.