Four girls with unilateral renal aplasia complicated by genital anomalies

Abstract

We report four girls with unilateral renal aplasia complicated by genital anomalies. The first case was diagnosed with molimina menstrualia at the age of 12 years. The second case was diagnosed with genital anomalies at the age of 12 years when an infection was associated with retention of blood in the right uterus. Since this time, magnetic resonance imaging was performed at the age of 6 years in girl with unilateral renal aplasia, and a genital organ abnormality was confirmed. Third and fourth cases were diagnosed with OHVIRA syndrome (obstructed hemivagina and ipsilateral renal anomaly syndrome) at the age of 6 years. They had gynecological consultations and have progressed without complications. Genitourinary abnormalities associated with unilateral renal aplasia, such as OHVIRA syndrome, are diagnosed at different times depending on age. If the diagnosis is delayed, endometriosis may develop from molimina menstrualia and lead to infertility. Therefore, diagnosing reproductive organ abnormalities early and preventing complications through proactive examinations are important.