Japanese journal of pediatric nephrology
Online ISSN : 1881-3933
Print ISSN : 0915-2245
ISSN-L : 0915-2245
Case Reports
Rituximab in combination with multidrug therapy for refractory steroid-resistant nephrotic syndrome: report of two cases
Yu Nouno Satoru MizumotoShuro NishioMikita YamamotoMariko SawadaKunihiko AyaNobuaki TakedaKenji WakiYoshio Arakaki
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JOURNAL OPEN ACCESS

2024 Volume 37 Pages 83-88

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Abstract

We encountered two cases of a 1-year-old boy with refractory steroid-resistant nephrotic syndrome (SRNS). Their treatment regimens included prednisolone and cyclosporine, but did not result in complete remission. After receiving rituximab, the boy in case 1 was able to maintain an incomplete remission with low-dose cyclosporine alone, and the boy in case 2 was able to maintain a complete remission without any medication. In both cases, no genetic abnormalities were found in the analysis. Rituximab may be effective in refractory SRNS without genetic abnormalities.

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© 2024 The Japanese Society for Pediatric Nephrology

この記事はクリエイティブ・コモンズ [表示 - 非営利 - 継承 4.0 国際]ライセンスの下に提供されています。
https://creativecommons.org/licenses/by-nc-sa/4.0/deed.ja
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