A Case of Angiomatoid Fibrous Histiocytoma That Occurred in the Left Forearm: Consideration of the Extent of Resection

Abstract

 Angiomatoid fibrous histiocytoma (AFH) is an intermediate-grade soft tissue tumor characterized by hemangioma-like histological features. We present a case of a 26-year-old woman with a 10 mm subcutaneous tumor on the left forearm. Initially, the lesion was suspected to be a benign tumor of cutaneous adnexal origin and was resected. Immunohistochemical and fusion gene analysis revealed AFH. Due to uncertainty regarding the extent of the disease, an enlarged resection was performed, followed by wound closure. Histopathological examination of the extended resection margins confirmed the absence of residual tumor cells. One year after surgery, no recurrence or metastasis was observed. This case emphasizes the diagnostic challenges associated with AFH and the importance of careful consideration of the extent of resection, particularly in cosmetically sensitive areas for young women.