Low-intensity Laser Treatment Stimulates Bone Formation and its Stimulatory Mechanism

Abstract

It has been reported that low-intensity laser treatment has many biological effects, and recent studies have examined the acceleration of bone regeneration by laser as it may hold great potential benefit for clinical therapy in orthopedics and dentistry. However, the biological effects of laser irradiation on bone are not fully understood. In order to use laser therapy for clinical treatment, it is necessary to prove its effects scientifically and to clarify the mechanisms by which it stimulates bone formation. We have been investigating the effects of laser irradiation on bone formation and the stimulatory mechanisms involved by in vivo and in vitro experiments. These results are reported in this review.