In-vivo Study of Low-Power Laser Irradiation On New Bone Formation of Rat Calvaria Defects
Influences of Different Power at Laser Irradiation
2001 Volume 12 Issue 1 Pages 2-9
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2001 Volume 12 Issue 1 Pages 2-9
Many low-power laser apparatuses have been developed, and their efficiencies have been reported for treatment of dentinal hypersensitivity or temporomandibularis. In addition, several reports indicated the application of a low-power laser. The purpose of this study was to investigate the effect of low-power laser irradiation on bone remodeling using rat calvaria with an artificially formed defect. Artificial bone defects of 4 mm in diameter were prepared by a round bur with a low-speed dental engine.
Ga-Al-As laser (830nm, 30mW, or 80mW) irradiation was applied to bone defects in right calvaria, as an experimental site, for 10 minutes once a day, and this procedure was carried out up to 1, 2, 3, 4, 5 or 6 weeks. Bone defects in left calvaria, without laser irradiation, were used as a non-irradiation site. Results obtained were as follows.
New bone formation was enhanced with 30mW laser irradiation. Particularly, 4-week irradiation showed the highest amount of new bone formation, compared with the control groups.
1. New bone formation was also enhanced with 80mW laser irradiation. Particularly, from 2-week to 4-week irradiation showed a significant difference between experimental groups, and control groups in the amount of new bone.
2. Camparing 30mW and 80mW irradiation, 80mW groups showed more new bone formation than 30mW groups after 3-week laser irradiation. However, there was no significant difference between 30mW and 80mW groups after 4-week irradiation.
(J. Jpn. Soc. Laser Dent. 12: 2-9, 2001 Reprint requests to Dr. MEZAWA)
