Abstract
Though amitriptyline is recognized as a primary treatment option for burning mouth syndrome, rumination about pain sometimes persists even after reduction of pain. A 58-year-old female with complaints of burning sensations of the tongue and mouth, and dry mouth sensation was referred to our clinic. With amitriptyline, the tongue pain was almost completely eliminated. However, two months later, symptoms recurred; she obsessively checked her tongue. Upon adding aripiprazole to amitriptyline, this obsessive symptom was quickly improved. Almost one year since the first visit, the oral symptoms have almost been relieved, without major side effects. This case suggests augmentation therapy of aripiprazole and amitriptyline may be effective for BMS patients with refractory rumination.
