頭頸部悪性腫瘍に対する化学放射線治療後の口腔乾燥症にロフラゼプ酸エチルとレバミピドが奏功した1例

宇津宮 雅史; 吉田 光希; Durga Paudel; 富野 貴志; 森川 哲郎; 神野 由貴; 松岡 紘史; 森谷 満; 安彦 善裕

doi:10.11268/jjpsd.37.1-2_17

Case Reports

Dry mouth due to chemoradiation relieved by ethyl loflazepate and Rebamipide: A case report

Masafumi Utsunomiya, Koki Yoshida, Durga Paudel, Takashi Tomino, Tetsuro Morikawa, Yoshitaka Kamino, Hirofumi Matsuoka, Mitsuru Moriya, Yoshihiro Abiko

Author information

Masafumi Utsunomiya
Division of Oral Medicine and Pathology, Department of Human Biology and Pathophysiology, School of Dentistry, Health Sciences University of Hokkaido
Oral Medicine Consultation Clinic, Health Sciences University of Hokkaido Hospital
Koki Yoshida
Division of Oral Medicine and Pathology, Department of Human Biology and Pathophysiology, School of Dentistry, Health Sciences University of Hokkaido
Oral Medicine Consultation Clinic, Health Sciences University of Hokkaido Hospital
Durga Paudel
Division of Oral Medicine and Pathology, Department of Human Biology and Pathophysiology, School of Dentistry, Health Sciences University of Hokkaido
Oral Medicine Consultation Clinic, Health Sciences University of Hokkaido Hospital
Takashi Tomino
Oral Medicine Consultation Clinic, Health Sciences University of Hokkaido Hospital
Tetsuro Morikawa
Division of Oral Medicine and Pathology, Department of Human Biology and Pathophysiology, School of Dentistry, Health Sciences University of Hokkaido
Yoshitaka Kamino
Division of Oral Medicine and Pathology, Department of Human Biology and Pathophysiology, School of Dentistry, Health Sciences University of Hokkaido
Sapporo Oral and Maxillofacial Surgery Clinic
Hirofumi Matsuoka
Division of Disease Control and Molecular Epidemiology, Department of Oral Growth and Development, School of Dentistry, Health Sciences University of Hokkaido
Division of Medical Psychology, Health Sciences University of Hokkaido Hospital
Mitsuru Moriya
Department of Psychosomatic Internal Medicine
Yoshihiro Abiko
Division of Oral Medicine and Pathology, Department of Human Biology and Pathophysiology, School of Dentistry, Health Sciences University of Hokkaido
Oral Medicine Consultation Clinic, Health Sciences University of Hokkaido Hospital

Keywords: dry mouth, ethyl loflazepate, rebamipide

RESEARCH REPORT / TECHNICAL REPORT RESTRICTED ACCESS

2023 Volume 37 Issue 1-2 Pages 17-19

DOI https://doi.org/10.11268/jjpsd.37.1-2_17

Details

Abstract

Radiation therapy is offered as a treatment option for head and neck cancer, but often results in dry mouth.
Pilocarpine has been used for treating dry mouth caused by radiation therapy.
We report a case of dry mouth relieved by ethyl loflazepate and Rebamipide after　chemoradiation therapy, for which Pilocarpine did not work.

Corresponding author

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