Abstract
We studied the efficacy of etizolam (Depas®) in 20 patients diagnosed as having glossodynia at the Department of Oral Surgery of Nagano Red Cross Hospital between February 1989 and January 1991.
To investigate the effects of this drug, we monitored 13 physical symptoms, 10 oral cavity symptoms, and four psychological symptoms. The CMI, Y-G, MAS and SRQ-D psychological tests were performed before and after administration to determine the psychological background of the subjects and any changes due to drug therapy.
There was a high efficacy rate of 94.1% for the overall improvement of symptoms. Most of the symptoms investigated showed a statistically significant improvement. Psychological testing showed a high incidence of neurotic tendency, emotional instability, and anxiety in the subjects. Side effects were noted in three out of 20 patients, but they were all mild and disappeared when administration was stopped.
These results suggest that etizolam is useful for the treatment of glossodynia.