ラットの罰訓練における海馬損傷の効果

岡市 広成; 斉藤 喜人

doi:10.4992/jjpsy.49.215

EFFECTS OF HIPPOCAMPAL LESIONS ON PUNISHMENT TRAINING IN RATS

HIROSHIGE OKAICHI, YOSHITO SAITO

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JOURNAL FREE ACCESS

1978 Volume 49 Issue 4 Pages 215-221

DOI https://doi.org/10.4992/jjpsy.49.215

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Published: November 20, 1978 Received: June 19, 1978 Available on J-STAGE: July 16, 2010 Accepted: - Advance online publication: - Revised: -
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Date of correction: July 16, 2010 Reason for correction: - Correction: ABSTRACT Details: Wrong : The present experiment was designed to determine the effects of hippocampal lesions on punishment training and to evaluate the spatial cognition hypothesis.
The hippocampectomized rats (hippocampals) and the operated control rats (controls) were each divided into runway and goal box punishment groups. The apparatus used was the elevated straight alley, which consisted of a white start box with a swinging door, a straight runway and a black goal box with a swinging door. An electric shock was delivered from either the floor of the runway or of the goal box. Four kinds of running time were measured; start box latency (SBL), runway running time (RRT), goal box entry time (GET) and goal box time (GBT).
After postoperative recovery periods, food motivated animals underwent 10 acquisition trials per day for 10 days. The eleventh day consisted of four reinforcement trials, one punishment trial and five postshock test trials. If an animal spent longer than 1, 200sec at any point of the alley on the sixth trial, it was placed into the goal box for 10sec. On the following trials, the criterion time was 120sec.
There were no differences between the hippocampals and the controls in any of the measures on training trials. Three factors analyses of variance were carried out for each of the four measures. Three factors were Operation (hippocampals vs. controls), Location of punishment (runway vs. goal box) and Experience of punishment (trial 4 vs. trial 6). The controls took significantly longer time on trial 6 than on trial 4 in all measures. The hippocampals did not show such hesitation in SBL, but did hesitate in other three measures. Operation × Experience interactions were significant in SBL, RRT & GET. The factor of Location had a significant effect to the runway punishment-controls. They spent longer times in the start box and on the runway than the other animals.
These results can be interpreted as follows; when the controls are placed in the start box, they recognize the place as a dangerous one which leads to the place where they were administered shock before, and they, therefore, hesitate to move forward from the start box. The hippocampals are not able to recognize this and, therefore, start without hesitation. However, when they recognize stimulus cues which were associated with punishment on the alley, they hesitate to go ahead. That is to say, these results can be considered to support the spatial cognition hypothesis.
Right : The present experiment was designed to determine the effect of hippocampal lesions on punishment training and to evaluate the spatial cognition hypothesis. Hippocampectomized and operated control rats were each divided into runway and goal box punishment groups. Food motivated animals were tested in the elevated straight alley on 10 acquisition days and 1 punishment day. Start box latency, runway running time, goal box entry time and goal box time were measured. The controls spent longer time in all measures on the postshock trial. The hippocampals showed no hesitation in the start box latency on the postshock trial, but they spent longer time in other measures. The location of punishment had significant effects only on the start box latency of the controls. These results support the spatial cognition hypothesis.

Abstract

The present experiment was designed to determine the effect of hippocampal lesions on punishment training and to evaluate the spatial cognition hypothesis. Hippocampectomized and operated control rats were each divided into runway and goal box punishment groups. Food motivated animals were tested in the elevated straight alley on 10 acquisition days and 1 punishment day. Start box latency, runway running time, goal box entry time and goal box time were measured. The controls spent longer time in all measures on the postshock trial. The hippocampals showed no hesitation in the start box latency on the postshock trial, but they spent longer time in other measures. The location of punishment had significant effects only on the start box latency of the controls. These results support the spatial cognition hypothesis.

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