Regulatory Trends, Changes in Scientific Findings and Standard Values, and Their Implications Regarding PFAS

Abstract

This study reviews the use, regulatory trends and changes in scientific findings and standard values regarding Per- and Polyfluoroalkyl Substances (PFAS), which are currently attracting attention both domestically and internationally. Currently, PFAS is a shift towards managed as “total PFAS” although there are industry stakeholders advocating for a prudent approach to swift regulation. In addition, in recent years, very low toxicity assessment values, such as TDI (Tolerable Daily Intake), for PFAS have been adopted on the basis of epidemiological studies, prompting a need to reassess toxicity assessment methodologies should be conducted. The discussion on total PFAS would be a good opportunity to consider risk assessment and management approach for other chemicals as well.