Nihon Bika Gakkai Kaishi (Japanese Journal of Rhinology)
Online ISSN : 1883-7077
Print ISSN : 0910-9153
ISSN-L : 0910-9153
Original Articles
Three Cases of Schwannoma Originated in the Nasal and Paranasal Sinus
Masayo HasegawaNaohiro YoshidaShingo MatsuzawaHiromi KanazawaYukiko Iino
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2014 Volume 53 Issue 2 Pages 77-84

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Abstract
We report three cases of schwannoma originating in the nasal and paranasal sinus. A 59-year-old female complained of right nasal obstruction due to right nasal tumor attached to the nasal septum. Histopathological analysis of the right nasal tumor showed that it was an Antoni type A schwannoma. En block tumor resection was performed endoscopically.The second case was a 72-year-old female who was diagnosed following MRI conducted as part of a periodic health examination. The tumor originated in the ethmoidal sinus and appeared as a round mass. CT revealed bone degeneration of the medial wall of the orbit. An intraoperative diagnosis of schwannoma without malignancy was made. The entire tumor was resected endoscopically. The resected tumor was diagnosed as an Antoni type A schwannoma on the basis of positive immunohistochemical results for the anti-S-100 antibody. There were no malignant findings.The third case was 34-year-old female who complained of right nasal obstruction. CT showed a soft tissue density mass occupying the entire right nasal cavity. We suspected schwannoma from biopsy. The tumor was removed completely by endoscopic sinus surgery. The tumor was originated from the anterior part of the nasal septum. The histopathological findings revealed it to be Antoni A and B type schwannoma.The three patients showed no tumor recurrence or metastasis after operation.
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© 2014 Japan Rhinologic Society
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