Abstract
Among all tumors of sinonasal origin, neoplasms of the nasal septum are rare, regardless of their benignity or malignancy. Squamous cell carcinoma of the nasal septum is extremely rare. Certain occupations and smoking are thought to be related to its carcinogenesis, and it is known to show a tendency for field cancerization. Therefore, these diseases often develop in patients who have already been treated for another head and neck cancer. As such, when we treat them, a limit to treatment may occur because of such previous therapy. In this manuscript, we report 2 patients with squamous cell carcinoma of the nasal septum who had already received previous therapy. We chose individualized treatment in accordance with each of their pathologies. Both of them could be detected by nasal endoscopy. Thus, when we treat patients with head and neck cancer, we should not forget careful inspection of the nasal cavity.