Abstract
Angioleiomyoma is a benign tumor that is seen in the head and neck region. We report a case of angioleiomyoma occurring in the nasal septum. A 65-year-old woman had received nasal continuous positive airway pressure (nCPAP) treatment for obstructive sleep apnea syndrome for 3 months. She visited our hospital
because of recurent epistaxis, and a physical examination revealed a soft mass in the left side of nasal septum. CT scan and MRI with enhancement showed a well-enhanced mass in the left side of nasal septum without bone destruction. Biopsy revealed angioleiomyoma. The tumor was excised by a transnasal approach. Histological and immunohistochemical findings yielded a definitive diagnosis of angioleiomyoma. Angioleiomyoma should be considered in the differential diagnosis of any well-circumscribed, hypervascular, soft-tissue mass arising in the submucosal tissue of the nasal septum. We believe that the angioleiomyoma was caused by the nCPAP treatment in this case. Therefore, it is important to check the upper airway including the nasal cavity during nCPAP treatment.