2016 Volume 55 Issue 4 Pages 515-523
Bisphosphonates are frequently used for the treatment of bone metastases, multiple myeloma, osteoporosis, and other bony diseases. Recent reports have described bisphosphonate-related osteonecrosis of the jaw (BRONJ) as a potentially serious complication related to the long-term use of these drugs despite their various benefits. An 86-year-old osteoporotic woman suffered from right cheek pain, nasal discharge, and discharge from the maxillary gingiva. She was diagnosed as having BRONJ with right sinusitis on the basis of exposed, necrotic bone in the right maxillary region, current bisphosphonate use, and no history of radiation therapy to the jaw. After 2.5 months of treatment with antibiotic therapy and discontinuation of bisphosphonate administration, a right subperiosteal orbital abscess appeared. We performed sequestrectomy, and endoscopic sinus surgery with drainage of the right subperiosteal orbital abscess. After surgery, the patient was doing well.
