Abstract
Messerklinger's extensive investigation into the anatomy, mucociliary clearance mechanism and pathology of recurrent sinusitis has clearly demonstrated that most infections of the paranasal sinuses are of rhinogenic origin. These infections which begin inside the nose spread into the paranasal sinuses.
Messerklinger's research clearly demonstrated that the health of the larger paranasal sinuses is completely dependent upon their pre-chambers through which they are connected to the anterior ethmoid and to the nasal cavity.
Messerklinger's surgical concepts have revolutionized the surgical treatment of patients with recurring sinusitis by enabling the surgeon to carry out a specifically targetted minimally invasive and functional endoscopic surgical resection.