Abstract
We report a case of acute renal failure after extraluminal injection of glycerin enema and discuss the side effects of glycerin enema. A woman in her sixties with anal prolapse complained of anal pain after bowel preparation for colonoscopy with administration of 120mL of 50% glycerin enema. She complained of epigastralgia and nausea 2 h after the enema. Brown urine was observed 10 h after the enema, and urine volume was 96mL/day by the next day. Laboratory data revealed evidence of hemolysis and renal dysfunction, and computed tomography showed air and edema around the rectum. Based on these findings, we made a diagnosis of acute renal failure caused by extraluminal injection of glycerin enema. Hemodialysis was performed 6 times over the course of 9 days, and haptoglobin was administered to prevent renal damage from hemolysis. Following this treatment, there was recovery of renal function and this normalized 2 months after the enema.
