Abstract
Small cell carcinoma of the prostate is a rare, highly malignant disease with a poor prognosis that often presents with metastatic lesions at the time of diagnosis. A previous study reported that neuroendocrine differentiation occurred during hormonal therapy for prostate cancer and progressed to small cell carcinoma. We encountered one case in which small cell carcinoma was diagnosed at the first visit and another case involving possible neuroendocrine differentiation.
