A case of inguinal pelvic Castleman’s disease complicated by lung cancer

Abstract

A 69-year-old male presented with a nodule in the left upper lobe observed on chest computed tomography (CT) scan, and a bronchoscopic biopsy confirmed the diagnosis of lung adenocarcinoma. Contrast-enhanced CT of the chest and abdomen revealed non-enhancing lymphadenopathy in the bilateral supraclavicular regions and intensely enhancing lymphadenopathy in the right inguinal and pelvic regions. PET/CT showed weaker FDG accumulation in the right inguinal and pelvic lymph nodes compared to the supraclavicular lymph nodes. Pathological diagnosis from a biopsy of the right inguinal lymph node confirmed mixed-type Castleman’s disease. When lymphadenopathy associated with malignant tumors cannot be determined as metastatic lesions, it is crucial to actively perform a biopsy.