Abstract
Because of sudden loss of consciousness, a eighty-one year old female was admitted to our hospital. No special findings suggestive of Sarcoidosis were obtained from either personal history, physical examination or laboratory studies including chest X-ray examination. On fourteenth hospital day, the patient died of pneumonia. On autopsy, diffusely disseminated sarcoid granulomas throughout many organs were revealed: the lungs, heart, liver, spleen, kidneys and the lymphnodes in bilateral pulmonary hila, paratracheal regions and along abdominal aorta. The granulomas detected in the pulmonary interstitium and peribronchial tissue were accompanied with the Langhans giant cells, but with scant epithelioid cells and lymphocytes. On the other hand, in the granulomas especially in the lymphnodes and the spleen, abundant proliferation of asteroid bodies, giant cells and epithelioid cells were observed. Despite of the lesions in the epicardium and myocardium, no arrhythmia was observed on EGG. Though the characteristic feature of multiorgan involvement in sarcoidosis was still revealed in such a aged patient, the lesions were histologically uneven throughout the organs involved.
