Abstract
A case of macroglobulinemia, 68-year-old male, is presented. The chest X-ray film revealed infiltrative-reticular shadows and pleural thickening especially in right lower field. The diagnosis was established by both characteristic monoclonal increase of IgM(L) in the serum and remarkable infiltrate of plasmacytoid-lymph-reticular cells in biopsied lung, pleura and lymph node tissues.
Pleuropulmonary lesions were responsive to cyclophosphamide, but not to chlorabmucil. The patient died in coma 1 year and 8 months after the first visit.