Abstract
1) Frequency distribution of normal values in clinical chemistry are regular and usually have narrow ranges.
2) Normal values have not only normal distributions but also non-Gaussian distributions.
3) Although the term “normal values” is seriously afflicated by conceptional problems, it is defined statistically as 95% of the range of healthy subjects.
4) Normal values have several factors of physiological variations including sex on uric acid, development on alkaline phosphatase, diet on triglyceride, exercise on creatine phosphokinase, and posture on serum protein.
5) Certain blood constituents vary chronically due to the environmental conditions. γ-GTP and triglyceride levels tend to increase chronically in males who drink habitually, and the CPK level decrease on hospitalization.
6) Certain blood parameters depend more on personal characteristics than on broad demongraphic factors. These findings indicate that its necessary to decide intra-individual normal values for clinical diagnosis.
