The Japanese journal of thoracic diseases
Online ISSN : 1883-471X
Print ISSN : 0301-1542
ISSN-L : 0301-1542
A Case Report of Lung Cancer with Prolonged Pleural Effusion after Pneumonectomy: The Significance of Sarcoid-like Lesions in Association with Malignant Tumors
Akitoshi TatsumiAkira FujioTadashi SatoKenji KasaharaTadashi NakajiAtoh MasudaAkira NonoyamaTerumasa KagawaTeruo Tachibana
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1980 Volume 18 Issue 2 Pages 112-117

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Abstract
A case of lung cancer with prolonged pleural effusion after pneumonectomy was presented. He was found to have a shadow 3×4cm. in size in the left lung field. Left pneumonectomy was performed on June 2, 1972, because of many swollen lymph nodes in the mediastinum. About 500ml. of bloody pleural effusion was removed once after a few months by means of thoracentesis after surgery, but a large amount of pleural effusion has remained for the past seven years. The reason why the pleural effusion did not disappear was not clear.
Pathological examination of hilar lymph nodes revealed non-caseating epithelioid cell granuloma without metastasis. However, clinical examination did not reveal evidence of generalized sarcoidosis, and the Kveim test was also negative.
Sarcoid-like lesions had been observed within malignant tumors and in the related regional lymphatics draining the primary neoplasm. Sarcoid-like lesion may be a type of tissue response indicating resistance of the body, and in this case, resistance to malignant tumors.
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© by The Japanese Respiratory Society
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