Abstract
A 78-year-old man was admitted to our hospital in October 1979 complaining of a tumor on his right leg with central ulceration. Except the skin lesion the results of his physical examination were normal and there was no peripheral lymphadenopathy. Routine laboratory examinations revealed normal differential leukocytic counts, urinalysis and blood chemistry. Biospy of the skin revealed non-Hodgkin's lymphoma. Subsquently radiation therapy was started and resulted in the regression of the skin lesion. In July 1980 multiple skin lesions developed, and VEMP therapy resulted in alternating regression and exacerbation. In June 1981 his chest roentgenogram showed multiple small nodular lesions. At the end of August 1981 he suffered cough, puta and fever. Fiberoptic bronchoscopy revealed a tumor occupying the bronchus (left B5). He died on September 7, 1981. At the autopsy his lung revealed multiple nodular lesions and a tumor obstructing left B4 and B5a. His autopsy diagnosis was extranodal non-Hodgkin's lymphoma.
Malignant lymphoma infiltrating the lung is not so rare but tumor formation in the bronchial lumen is extremely rare. On fiberoptic bronchoscopy this endobronchial mass was seen without invasion in the surrounding bronchus. The mass consisted of malignant lymphoma cells (pleomorphic type of diffuse lymphoma).