The Japanese journal of thoracic diseases
Online ISSN : 1883-471X
Print ISSN : 0301-1542
ISSN-L : 0301-1542
Study on Changes in the Bronchial and Pharyngeal Mucosa by Longterm Inhalation of Beclomethasone Dipropionate
Norio KiharaSohei MakinoKazuhiko Soejima
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1984 Volume 22 Issue 4 Pages 304-310

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Abstract
Bronchial mucosa biopsies from nine patients with bronchial asthma were examined by light and electron microscopy after 2 to 6 years of daily therapy with beclomethasone dipropionate by aerosol inhalations. Biopsies revealed no changes referrable to treatment.
Pharyngeal mucosa biopsies from five out of none patients examined by electron microscopy also revealed no changes referrable to treatment. Candida albicans was not detected in sputum cultures performed after the bronchoscopic examinations. This study showed no abnormal findings which appeared to be caused by inhalation of beclomethasone dipropionate.
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© by The Japanese Respiratory Society
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